Menstrual cycle effects on the dexamethasone suppression test in major depression
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چکیده
منابع مشابه
Menstrual cycle effects on the dexamethasone suppression test in major depression.
Patients with major depressive disorder (MDD) fiequently exhibit dysregulation of the hypothalamo-pituitary-adrenal (HPA) axis reflected in elevated basal cortisol levels as well as resistance to feedback inhibition, which is typically manifested by resistance to suppression by dexamethasone (Carroll et al 1981; Stokes and Sikes 1988). Alterations in and interactions between the HPA and hypotha...
متن کاملDexamethasone Suppression Test for Major Depression
Overnight post dexamethasone plasma Cortisol levels were estimated in thirty patients of major depression and 30 controls. The cut-off point after which post dexamethasone plasma Cortisol level could be considered abnormal, in patients of major depression, has been worked out at 15 μg/dl in the present study. The results are discussed.
متن کاملDexamethasone Suppression Test in Depression
Baseline plasma Cortisol levels and response to dexamethasone in a group of twenty five patients with ma) or depressive disorder (MDD) and a control group of twenty five patients with psychiatric diagnoses other than MDD were estimated. The results of our study show that dexamethasone suppression test (DST) is a useful diagnostic aid in MDD with melancholia with a sensitivity of 46% and specifi...
متن کاملRevisiting the Dexamethasone Suppression Test in unipolar major depression: an exploratory study
BACKGROUND Important methodological questions still exist concerning the Dexamethasone Suppression Test (DST), including the possibility of a better way of interpreting it. The aim of the present study was to explore the feasibility of an alternative way of interpreting DST results. METHODS A total of 50 patients with major depression aged 41.0 +/- 11.4 years old participated in the study. Pa...
متن کاملChronic caffeine consumption and the dexamethasone suppression test in depression.
Acute caffeine administration increases cortisol and converts the dexamethasone suppression test (DST) to nonsuppression in normal humans; data concerning chronic administration as well as effects in depressed patients are minimal. To determine whether caffeine intake influenced DST results in depression, we retrospectively studied the relationship between regular daily caffeine consumption and...
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ژورنال
عنوان ژورنال: Biological Psychiatry
سال: 1991
ISSN: 0006-3223
DOI: 10.1016/0006-3223(91)90271-m